According to The Guardian, Applegate made the announcement in an episode of the MeSsy podcast recorded with fellow actor Jamie-Lynn Sigler and posted to YouTube on Tuesday. The report describes Applegate's reaction as unnerving and really confusing.
The disclosure follows Applegate's public advocacy for multiple sclerosis awareness and her account of living with the condition in a memoir published in March, background reported by The Guardian.
The Guardian's report does not explain how the alleged misdiagnosis was discovered or identify Applegate's current diagnosis. The supplied account is based on her reported podcast statement and does not include independent or official corroboration.