Christina Applegate says MS diagnosis was wrong as symptoms remain unresolved

Applegate said the new information left her “back at square one” because she had not improved and had become worse in some ways. Her account changes the public understanding of a multiple sclerosis diagnosis that had been reported in 2021, but the supplied evidence does not identify her actual medical condition or explain the medical basis for the revised diagnosis.

She said she continues to experience symptoms associated with MS despite the revised information about her diagnosis. According to PBS NewsHour’s reporting of Applegate’s account, she sometimes needs a wheelchair to travel from a car to a doctor’s office because she cannot walk that distance.

The disclosure was made on MeSsy, the podcast Applegate co-hosts with Jamie Lynn Sigler. Reports said Applegate had lived with the MS diagnosis for years after receiving it in 2021 before learning that it was wrong.

The available reporting presents the diagnosis change primarily through Applegate’s own comments. It does not provide medical records, name an alternative condition or identify a physician independently confirming the revised diagnosis. What is established is that Applegate says the MS diagnosis was incorrect while her serious symptoms continue, leaving the underlying cause unresolved in the supplied evidence.