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An Ebola vaccine clinical trial has begun in the Democratic Republic of the Congo to test vaccines against the Bundibugyo strain during an ongoing outbreak, according to reports confirmed by the World Health Organization.

The trial’s start was reported by Medical Xpress, Forbes Business, The Hindu and Al Jazeera. The World Health Organization announced or confirmed the launch, with the supplied reports placing it around October 23, 2026.

The Hindu reported that Ervebo, a vaccine approved for the Zaire strain, is being tested for possible cross-protection against Bundibugyo. Al Jazeera reported that the trial is intended to assess vaccine safety, efficacy and immunogenicity.

Forbes Business reported that the outbreak’s death toll was nearing 4,700 and described it as the Democratic Republic of the Congo’s deadliest Ebola outbreak. That death toll and characterization were not quantified or repeated by the other supplied reports.

SOURCES

  1. The HinduEbola vaccine trial begins in DR Congo
  2. Medical XpressEbola vaccine trial begins in DR Congo
  3. Al JazeeraWHO announces start of Ebola vaccine clinical trial in DR Congo
  4. Forbes BusinessEbola Vaccine Trials Begin In DRC As Death Toll Nears 4,700